Methotrexate drug plug and play role in Human body

Abstract

MTX functionally acts as antimetabolite drugs, interfered folic acid metabolism, used as an anti-proliferative drug for abnormal cell growth inhibition such as tumor cell or cancer cell, chronic inflammation, ectopic pregnancy, psoriasis disease, multiple sclerosis disease, Crohn disease, sarcoidosis, rheumatology related disorder, and autoimmune disease. Newly synthesized MTX derivatives via organic Schiff base technique could be prepared, used against different disorder.