Accuracy of Magnetic Resonance Cholangiopancreatography (MRCP) in Comparison with Endoscopic Retrograde Cholangiopancreatography (ERCP) for Diagnostic Choledocholithiasis

Abstract

Objective: To determine the diagnostic accuracy of MRCP for the diagnosis of choledocholithiasis keeping ERCP as gold standard.

Methodology: The Cross sectional study was planned in department of radiology, PIMS, Islamabad from August 2021 to July 2022. All patients suspected of choledocholithiasis will be diagnosed on the basis of symptoms, laboratory findings, and radiological results. Hematologic and biochemical tests will be performed on all patients shortly after admission. Inclusion of 100 suspected patients of choledocholithiasis through non-probability consecutive sampling. MRCP will be performed and followed by the ERCP. Patient demographic data, symptoms associated with choledocholithiasis, comorbidity history, laboratory profiles, and final diagnoses based on MRCP and ERCP results were recorded using a self-designed form.

Results: The average age of the patient was 54.63±11.8 years. The male to female ratio in the study was 1.27:1. Derange liver function test was observed in 48% patients. Colicky was found in 39% cases, abdominal pain was observed in 86% and intermittent jaundice was observed in 33% patients. The diagnostic analysis of MRCP showed that the MRCP had a sensitivity of 98.4%, specificity 89.7%, positive predictive value 94.9% and negative predictive value 87.8%.

Conclusion: MRCP had a high sensitivity and specificity for detection of choledocholithiasis.