The Relative Efficacy of Topical and Systemic Antibiotic Therapy in Preventing the Development of Pyogenic Granulomas in Burn Patients

Abstract

Pyogenic granuloma (PG) is a benign vascular tumor commonly seen in children, typically emerging on the skin or mucosal surfaces. This case series examines ten instances of PG following second-degree burns, presenting unique clinical features and treatment responses. PG, often a result of trauma rather than infection, can mimic other vascular lesions and requires accurate diagnosis to distinguish it from conditions like Kaposi's sarcoma and deep mycosis. The series includes cases of burn injuries caused by various substances, such as hot milk, oil, and boiling water, leading to PG formation. Treatment strategies varied based on the severity and complications of the burns, including bacterial and fungal infections. Standard burn care, including topical antibiotics and dressings, was employed initially, with advanced therapies and surgical interventions applied as needed. Notably, individualized treatment based on microbiological results improved outcomes significantly. This study underscores the necessity for precise diagnosis and tailored therapy to manage burn-related PG and associated infections effectively. Future research should focus on standardized burn care protocols and the impact of antimicrobial treatments on burn healing.