Correlation of Glycated Albumin With Glycated Hemoglobin as a Marker for Assessment of Beta Cell Function in Type 2 Diabetes

Abstract

Objective: To evaluate a relationship between Glycated Albumin and Hba1c in comparison to Serum as predictor for Beta Cell Function in and type-2 diabetes population.

Methodology: A descriptive cross-sectional study was conducted among 163 diabetic patients, aged 30 to 70 years and both genders who presented at the Lumhs Civil/Jamshoro OPD and wards with diagnosis of Diabetes Mellitus for at least 6 months or more. A 5cc blood sample was collected from each participant using EDTA tubes for the analysis of glycated albumin and glycated hemoglobin. All data collection procedures were conducted with utmost regard for participant privacy and confidentiality using study proforma and spss version 26 was used for analysis.

Result: The mean age of the participants was 62.06±11.03 years. Out of 163 patients 50.3% were male and 49.6% were female. Correlation analyses of the findings had revealed that a significant correlations p<0.001was present between HbA1C levels and glycated hemoglobin levels whereas a significant relation was also found between Body Mass Index and HbA1C and glycated hemoglobin levels.

Conclusion: The study concludes that both glycated albumin were recorded high among diagnosed type 2 diabetic mellitus patients, with a strong correlation between HbA1C levels and glycated hemoglobin levels whereas a significant relation was also found between Body Mass Index and HbA1C and glycated hemoglobin levels.