Correlation of Triglycerides to Glucose Index With the SYNTAX Score in Patients of Acute Coronary Syndrome

Abstract

Objective: To determine the severity of triglycerides to glucose index and its correlation with the SYNTAX score in patients presenting with ACS.

Methods: An analytical type of cross-sectional study was done in the Department of Cardiology CPEIC, Multan. 200 patients with ACS were enrolled, their fasting triglycerides and glucose were sent, and all underwent coronary angiography during hospitalization. The Triglycerides-Glucose index was calculated, and after descriptive statistics, the proportion of ?8.8 TyG was determined. Following it, the correlation of TyG with the syntax score was measured and a p-value of ? 0.05 was found significant. Effect modifiers were controlled by data stratification.  

Results: There were 162 (81.0%) male, mean age 46.52±14.41 years and mean BMI was 24.43±4.07 kg/m². 119 (59.5%) patients had severe ?8.8 TyG, mean SYNTAX score I was 24.01±2.29, and mean TyG index was 8.71±0.92.A significant positive correlation between the Syntax score and TyG index, ( r: 0.924, p<0.001). After data stratification correlation was high and significant in males, age group of 51-65 years, BMI from 25 to 29.9 kg/m², smokers, hypertensives, and diabetic patients

Conclusion: Triglyceride Glucose Index is positively correlated with syntax score. TyG being an inexpensive and quick tool can be used as the coronary artery disease severity predictor.