Colonizer to Drug Resistant isolate, What is Happening to our Staphylococcus Aureus?

  • Muhammad Zain-Ul- Abidin Medical Officer Rural Health Centre Khalaspur1,2 3People’s University of Medical and Health Sciences,Nawabshah
  • Talha Rashid Medical Officer Rural Health Centre Khalaspur
  • Ayesha Waheed People’s University of Medical and Health Sciences,Nawabshah
  • Farhan Rasheed Assistant Professor Pathology, Microbiology Section, Pathology department, Allama Iqbal Medical College & Jinnah Hospital (AIMC&JHL) Lahore
  • Muhammad Ilyas
  • Maqsood Ahmad M.Phil Medical Laboratory sciences, Medical Laboratory Scientist, University of Health Sciences, Lahore

Abstract

Objective: To evaluate resistant trend of multiple antimicrobial agents against Staphylococcus aureus isolates along with its prevalence. 
Material and Methods: This prospective descriptive study was carried out in the department of microbiology Allama Iqbal Medical College Lahore from 1st January 2015 to 25 may 2016. Simple random technique was used, and 4570 clinical samples (Pus, blood, pleural fluid, tracheal aspirate, urine, sputum, HVS) were received from ICU, Surgical Unit, Medical Unit and OPD for culture sensitivity testing, antimicrobial resistant trend was tested according to CLSI guidelines 
Results: Maximum isolates were recovered from surgical unit 31.9%, sample-wise maximum isolates were recovered from pus samples 26.8%. age group and genderbased distribution showed among male’s high isolation rate was observed in 21-40 years while in females 41-60-year age group. Every isolate was (100%) susceptible to linezolid, vancomycin and teicoplanin, cotrimoxazole also showed very low rate of drug resistance only 8.3%, while penicillin Doxycycline, Ciprofloxacin, Erythromycin showed 95.9%,69.8%55.4% and 48.2% drug resistance respectively, 43-45% drugresistant rate observed in case of Co-amoxiclave, Methicillin, Gentamicin, Fusidic Acid, Amikacin, and Clindamycin 
Conclusion: Linezolid, Vancomycin, and Teicoplanin are best therapeutic Choices against Staphylococcus aureus associated infections.

Published
2018-05-17
How to Cite
ZAIN-UL- ABIDIN, Muhammad et al. Colonizer to Drug Resistant isolate, What is Happening to our Staphylococcus Aureus?. Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University, [S.l.], v. 14, n. 1, p. 74-78, may 2018. ISSN 1815-2287. Available at: <https://apims.net/index.php/apims/article/view/71>. Date accessed: 22 oct. 2018.
Section
Original Articles