Nuetrophil-To-Lymphocyte Ratio (NLR) as a Predictor of Acute Appendicitis
Keywords:Acute, Neutrophil, Lymphocyte, Appendix, Histopathology
Objective: To determine the diagnostic accuracy of (NLR) neutrophil-to-lymphocyte ratio to prognosticate severe/ complicated appendicitis by taking histopathology of the appendix as a gold standard.
Methodology: This cross-sectional validation study was conducted at the department of surgery and western vascular institute, University College Hospital Galway, Ireland
retrospectively for a period of 6 months i.e. from 05/06/2016 to 05/01/2016. For sampling in this study, non-probability purposive convenience technique was used. An informed consent was taken from each patient. All data were analyzed on SPSS version 21.
Results: The mean age of patients in this study was 29.15Â±9.54 years, the ratio of male to female was 1:1.7. The sensitivity, Specificity was 97.1% and 25.2% respectively and diagnostic accuracy of NLR was 38.7% taking histopathology as gold standard.
Conclusion: According to our study results the (NLR) neutrophil-to-lymphocyte ratio is a highly sensitive tool to predict severe/ complicated appendicitis by taking histopathology as the gold standard, but with low value of diagnostic accuracy in terms of specificity.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.