Determining the Rate of COVID-19 Infection in Post-Vaccinated Individuals and Its Severity


  • Azmat Ali Head of Medicine Department, KRL Hospital Islamabad
  • Abdur Rahman Butt



Vaccine, Immunity


Objective: To assess the incidence of Covid-19 infection in people who were vaccinated and to categorize disease severity.

Methodology: This cross sectional study was carried out at the Department of Medicine, KRL Hospital, Islamabad from September 2021 to February 2022. Individuals above 18 years of age, and fully vaccinated were included in the study. Using a pre-validated interview based close ended questionnaire data was collected, informed consent was obtained, and data was analyzed using SPSS Statistics 23. The severity of COVID-19 was determined by applying the WHO severity definitions.

Results: The study included 362 individuals. 55.00% were males and 45.00% were females. The minimum age was 20 years and maximum 76 years with a mean of 45.73 ± 14.919. 27.1% of the participants had co morbidities, of which diabetes was the most frequent (59.18%). Majority (37.84%) individuals received Sinopharm vaccine. This was followed by Pfizer (24.58%) and Moderna (13.82%). 158 patients (43.65%) reported infection with covid-19. Out of 158, 41 (25.94%) had severe infection and 9 (5.70%) had critical infection on WHO criteria.

Conclusion: A substantial proportion of fully vaccinated individuals suffered from Covid-19 infection (43.64%). Pfizer was the most effective vaccine in preventing infection (79.77%). While Sinopharm was the least effective (41.60%). However, vaccination was effective in preventing severe and critical infection in a significant number of patients (86.18%).






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