EFFECT OF HYPERBARIC BUPIVACAINE INJECTION SPEED OF 20 VS 40 SECONDS ALONGWITH PRELOAD COLLOID ON HEMODYNAMICS IN CESAREAN WOMEN

Comparing 20 vs 40 seconds bupivacaine speed along with preload colloid for hemodynamics in c-section

Authors

  • Saleem Abbasi International Research Force
  • Beena Rani Associate Anesthetist, Federal General Hospital, Islamabad
  • Syed Mujahid Gillani Intensivist, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad
  • Salman Shafi Koul Assistant Professor, Critical Care Medicine, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad
  • Khurram Liaqut Associate Anesthetist, Federal General Polyclinic Hospital, Islamabad
  • Ussama Bilal Medical Officer, Critical Care Medicine, Shahida Khaliq Health Centre, Islamabad
  • Mir Muhammad Hassan Bullo Medical Director, Federal General Hospital, Islamabad
  • Abida Tauheed Resident Physician, Federal General Hospital, Islamabad
  • Sana Umer Assistant Professor, HITEC School of Medicine, Wah Cantt

Abstract

Introduction: Hemodynamic derangement after spinal anesthesia in cesarean section is quite common. If not controlled, hypotension and other hemodynamics can lead to serious threats to mother and child. The current study aimed to compare 20 vs 40 seconds bupivacaine speed along with preload colloid for hemodynamic control in cesarean women.

Objective: To compare 20 seconds vs 40 seconds hyperbaric bupivacaine speed along with preload colloid in the prevention of hemodynamics like hypotension in cesarean women.

Study design: Randomized controlled trial

Study setting: Anesthesia Department, Federal General Hospital, Islamabad

Methods: Study duration was 6 months from 28th November to 30th May 2023. Total 100 women undergoing cesarean section were systematically randomly equally allocated to hyperbaric bupivacaine injection in 20 seconds speed (n=50) or 40 seconds speed (n=50) along with preload colloid. Study outcome was hemodynamics (hypotension, heart rate and side effects) between two groups. Study was approved by hospital ethics committee and written consent was administered. Data was analyzed in SPSS version 25.0.

Results: Patients demographics and gestational history was found comparable in the two groups. The average systolic and diastolic BP varied from 4 to 15 minutes after anesthesia induction. The incidence of hypotension was significantly high in the 40 seconds preload colloid group 27 (54.0%) compared to 12 (24.0%) in the 20 seconds group (p-value, <0.001). Rate of nausea was found similar in two study groups.

Conclusion: Incidence of hypotension was significantly high in 40 seconds group compared to 20 seconds injection speed of bupivacaine in this study.

Published

2024-10-22

Issue

Section

Original Articles