Nuetrophil-To-Lymphocyte Ratio (NLR) as a Predictor of Acute Appendicitis

Authors

  • Sadia Tasleem Department of Surgery and Western Vascular institute, UCHG, Ireland
  • Nadia Gulnaz Department of General and Upper GI Surgery, UCHG, Ireland
  • Aamir Afzal Bio-Statistician Foundation University Islamabad
  • Don Courtney Department of Surgery and Western Vascular institute, UCHG, Ireland

DOI:

https://doi.org/10.48036/apims.v14i1.72

Keywords:

Acute, Neutrophil, Lymphocyte, Appendix, Histopathology

Abstract

Objective: To determine the diagnostic accuracy of (NLR) neutrophil-to-lymphocyte ratio to prognosticate severe/ complicated appendicitis by taking histopathology of the appendix as a gold standard.
Methodology: This cross-sectional validation study was conducted at the department of surgery and western vascular institute, University College Hospital Galway, Ireland
retrospectively for a period of 6 months i.e. from 05/06/2016 to 05/01/2016. For sampling in this study, non-probability purposive convenience technique was used. An informed consent was taken from each patient. All data were analyzed on SPSS version 21.
Results: The mean age of patients in this study was 29.15±9.54 years, the ratio of male to female was 1:1.7. The sensitivity, Specificity was 97.1% and 25.2% respectively and diagnostic accuracy of NLR was 38.7% taking histopathology as gold standard.
Conclusion: According to our study results the (NLR) neutrophil-to-lymphocyte ratio is a highly sensitive tool to predict severe/ complicated appendicitis by taking histopathology as the gold standard, but with low value of diagnostic accuracy in terms of specificity.

Published

2018-05-17

Issue

Section

Original Articles