Comparative Study of Single- Versus Split-Dose Polyethylene Glycol Electrolyte Solution Before Undergoing Colonoscopy

Authors

  • Salman Javed Assistant Professor Gastroenterology Services Institute of Medical Sciences, Lahore
  • Najam Us Sehar Assistant Professor Gastroenterology Sir Ganga Ram Hospital, Lahore
  • Sarah Samreen Medical Unit-III Sir Ganga Ram Hospital Lahore
  • Mohsin Raza Senior Registrar Medical Unit-III Sir Ganga Ram Hospital, Lahore
  • Qamar Sajad Senior Registrar Medical Unit-I Sir Ganga Ram Hospital, Lahore
  • Amber Saleemi Woman Medical Officer Mayo Hospital Lahore

DOI:

https://doi.org/10.48036/apims.v18i1.599

Keywords:

single dose, polyethylene glycol electrolyte solution, colonoscopy

Abstract

Objective: To compare the outcome of consumption of a single versus split-dose polyethylene glycol electrolyte solution in patients undergoing colonoscopy in the morning.

Methodology: A randomised controlled trial was conducted at the Department of Gastroenterology, Sir Ganga Ram Hospital, Lahore from April to July 2021. A total of 274 patients undergoing colonoscopy, who fulfilled the selection criteria were included through a "non-probability, consecutive sampling technique". The patients were randomly divided into two groups. In group A, single dose of PEG was administered. Group B was administered a split dose of PEG which was to be consumed in two parts, 1st in evening before colonoscopy and the second in the morning. The patients then underwent colonoscopy. Efficacy was labelled if adequate cleaning of the intestines and BBPS score of ≥6 were achieved during colonoscopy. All this procedure was noted on a proforma. Data was entered and analyzed by using SPSS version 20.0.

Results:  In the single dose group, the mean age of patients was 45.15 ± 13.37 years, 68 (49.6%) patients were male, 69 (50.4%) patients were female, efficacy of the procedure was achieved in 54 (39.4%) patients, and the mean BBPS score was 4.99 ± 0.90 . In the split dose group, mean age of patients was 49.85 ± 11.38 years, 56 (40.9%) patients were male, 81 (59.1%) patients were female, efficacy of the procedure was achieved in 137 (100%) patients and the mean BBPS score was 7.61 ± 0.49 . The difference in both groups was highly significant (p-value < 0.0001).

Conclusion: A split dose is thus more efficacious and acceptable than single dose of polyethylene glycol electrolyte solution given for bowel preparation.

Published

2022-04-28

Issue

Section

Original Articles