Early Bubble Continuous Positive Airway Pressure Therapy for Premature Neonates with Respiratory Distress Syndrome


  • Nahdia Zaman Rawalpindi Medical University, Rawalpindi
  • Jawaria Zia
  • Anam Zafar




Objective: To determine the improved outcomes by early introduction of bubble continuous positive airway pressure (CPAP) in preterm neonates.

Methodology: This descriptive case series wasconducted in NICU of Shifa International Hospital, Islamabad, Pakistan for a period of six month from 12thSep 2016 to 12thMarch 2017 after ethical approval. Around 90 preterm infants were enrolledwith gestational age of 28 to 37 weeks and with the clinical features of Respiratory Distress Syndrome (RDS). In the group failing CPAP the severity of RDS and fio2 requirement greater than 50% was noted.

Results: The mean gestational age was32.39±2.69and the mean birth weight was1827±532.97g.The median age to start CPAP was 5.27h of life and 10 babies had failed CPAP.Male preponderancewas likely to fail CPAP in present research. More than 80% of the group that failed CPAP had a Fio2 requirement greater than 50%,and 89% of the infants failing CPAP had severe RDS proven radiologically as well as clinically.

Conclusion: CPAP is of valuable importance in low resource countries with lack of ventilators and provides adequate and conservative method of treatment of mild to moderate RDS for preterm neonates, however in cases of severe RDS intubation and mechanical ventilation is often necessary.





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