Dyslipidemias in Hepatitis C Virus Infection at Isra University Hospital Hyderabad

Abstract

Objective: To determine the incidence of dyslipidemias in hepatitis C virus infected patients presenting at Isra University Hospital Hyderabad.

Methodology: The descriptive study was conducted at the Department of Gastroenterology, Isra university Hospital and Hyderabad from June 2017 to December 2017. All the patients with Anti hepatitis C virus (HCV) positive for >6 months, aged between 18 years to 60 years of both gender were included in the study. Fasting blood samples were taken from these patients and sent to the Hospital diagnostic laboratory for lipid profile. The tests were collected on reporting date. All the data was entered on the proforma by researcher himself. Data was analyzed on computer using SPSS software version 20.

Results: Total 80 patients were enrolled and mean age of the patients was 46.52+7.64 years. Male were found in majority 48(60.0%). Out of all (13.2%) patients were obese. Over all mean of total serum cholesterol was 180.04±13.12mg/dl, mean of serum triglyceride was 130±10.23 mg/dl, HDL mean was 30.23±5.55mg/dl, and mean of LDL was 125.42±9.53mg/dl. Dyslipidemia was 31(38.8%) out of all study subjects. Age >40 years and BMI >30 were significantly associated with dyslipidemia (p=0.001). However, no significant difference was found in dyslipidemia according to gender (p=0.818).

Conclusion:  It is concluded that the dyslipidemia was highly prevalent as 38.8% in HCV infected patients. Old age, smoking and BMI >30 were significantly associated with dyslipidemia. No significant impact of gender on dyslipidemia in HCV infected patients.